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M9490478.TXT
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1994-09-19
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Document 0478
DOCN M9490478
TI [Neuroradiological findings in perinatally HIV-infected children]
DT 9411
AU Spreer J; Enenkel-Stoodt S; Funk M; Fiedler A; de Simone A; Hacker H;
Radiologische Abteilung, Universitatsklinik Koln.
SO Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1994
Aug;161(2):106-12. Unique Identifier : AIDSLINE MED/94331627
AB The neuroradiological studies (CT, MRI, angiography) in 21 children with
perinatal HIV infection were reviewed retrospectively. No patient showed
an intracranial mass lesion; after intravenous contrast medium
application there was no case with disturbed blood-brain barrier. Common
non-specific findings were atrophy and delayed myelination. In 7 cases
atrophy was combined with multifocal nearly symmetric white matter
lesions, which characteristically spared the U-fibres. Further findings
included an intramedullary ring-shaped structure in the cervical cord,
an AIDS-associated vasculopathy and symmetric calcifications in the
basal ganglia. The spectrum of neuroradiological findings in paediatric
AIDS patients differs from that in adults. Knowledge of these
age-specific findings is important because the number of HIV-infected
children is rising.
DE Age Factors Atrophy Basal Ganglia/PATHOLOGY Brain/PATHOLOGY Central
Nervous System/*RADIOGRAPHY Cerebral Angiography Child Child,
Preschool English Abstract Female Human HIV
Infections/DIAGNOSIS/*RADIOGRAPHY Infant Magnetic Resonance Imaging
Male Retrospective Studies Spinal Cord/PATHOLOGY Tomography, X-Ray
Computed JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).